1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, ethyl ester
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
CAS: 503614-91-3
Molecular Formula: C27H28N4O5
1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, ethyl ester - Names and Identifiers
1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, ethyl ester - Physico-chemical Properties
| Molecular Formula | C27H28N4O5 |
| Molar Mass | 488.54 |
| Density | 1.34 |
| Melting Point | 175 - 180°C |
| Boling Point | 758.7±60.0 °C(Predicted) |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.001Pa at 25℃ |
| Appearance | Solid |
| Color | White to Pale Beige |
| pKa | 0.78±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Use | This product is for scientific research only and shall not be used for other purposes. |
1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, ethyl ester - Reference Information
| LogP | 172 at 22.8℃ |
| introduction | 1-(4-methoxyphenyl) -7-oxo-6-[4-(2-oxopiperidine-1-yl) phenyl]-4,5,6, 7-tetrahydro-1H-pyrazolo [3,4-C] Pyridine-3-carboxylic acid ethyl ester is an intermediate for the preparation of apixaban. apixaban is an antithrombotic drug. It is a direct inhibitor of factor Xa jointly developed by Bristol-Myers Squibb and Pfizer. It was approved for listing in the European Union in March 2011, and F DA approved the drug for listing in the United States in December 2012. |
| Use | 1-(4-methoxyphenyl) -7-oxo-6-[4-(2-oxopiperidine-1-yl) phenyl]-4,5,6, 7-tetrahydro-1H-pyrazolo [3, ethyl 4-C] pyridine-3-carboxylate is used in the synthesis and preparation of the drug Ridecivir apisaban. |
Last Update：2024-04-09 20:52:54
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Product Name: 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester Request for quotationCAS: 503614-91-3
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